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Preparation of varicella‐herpes zoster immunoglobulin
Author(s) -
Janot C.,
Stoltz JF.,
Avenard G.,
Perrier P.,
Schooneman F.,
Streiff F.
Publication year - 1981
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1981.21682085765.x
Subject(s) - medicine , antibody , titer , shingles , virology , immunology , antibody titer , population , virus , environmental health
The efficacy of zoster immunoglobulin in prophylaxis of varicella and herpes zoster is reported by many authors. The screening for zoster's antibodies is performed in the blood donor population and in persons convalescing from herpes zoster. The results show that 25 per cent of blood donors and 83.5 per cent of convalescents, respectively, have CF antibody titer of 16. Varicella zoster immunoglobulin prepared by alcohol fractionation has a fluorescent antibody titer of 1,024 and a CF antibody titer of 512. These results are discussed and compared with those of the literature.