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Gram‐Negative Sepsis Treated with Neutrophils Collected Exclusively by Intermittent Flow Centrifugation Leukapheresis
Author(s) -
Strauss R. G.,
Goedken M. M.,
Maguire L. C.,
Koepke J. A.,
Thompson J. S.
Publication year - 1980
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1980.20180125045.x
Subject(s) - leukapheresis , sepsis , antibiotics , medicine , centrifugation , neutropenia , immunology , microbiology and biotechnology , intensive care medicine , chemotherapy , chemistry , biology , genetics , stem cell , chromatography , cd34
The effectiveness of neutrophils prepared for transfusion by intermittent flow centrifugation leukapheresis (IFCL) as treatment for serious bacterial infections in neutropenic patients has not been documented in the literature. Their value, in fact, has been questioned. We report that IFCL neutrophils are similar to cells prepared by other techniques in the ability to support neutropenic patients with culture‐proven, gram‐negative sepsis unresponsive to antibiotics.