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A Strong Antibody Reacting with Enzyme Modified E Positive Red Blood Cells
Author(s) -
Heistø H.,
Fagerhol M. K.
Publication year - 1979
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1979.19580059806.x
Subject(s) - antibody , papain , enzyme , trypsin , red blood cell , titer , chemistry , antibody titer , immunology , microbiology and biotechnology , biology , biochemistry
A high titer antibody was discovered in a healthy young man of blood group A 1 R 2 r. The antibody strongly agglutinated all E positive red blood cells including his own, which had been modified by papain, ficin and bromelin, but only very weakly when modified by trypsin. The antibody was shown to be an IgM antibody. It did not react with unmodified red blood cells.