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Effects of Prolonged Room Temperature Holding of Whole Blood Intended for Preparation of Components
Author(s) -
Kahn R. A.,
Johnson R. K.,
Heaton W. A. L.
Publication year - 1979
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1979.19580059804.x
Subject(s) - platelet , whole blood , blood preservation , hemoglobin , blood component , medicine , yield (engineering) , blood collection , red blood cell , blood bank , chemistry , surgery , andrology , intensive care medicine , immunology , materials science , emergency medicine , metallurgy
Current FDA regulations require that platelet concentrates must be prepared within four hours of whole blood collection. To determine if this time period was critical for the harvesting of viable platelets and other blood components, whole blood was held at room temperature for four, six or eight hours after which various components were prepared. Our results indicate that up to eight hours storage had no detrimental effect on platelet yield, recovery in vivo or lifespan. AHF activity, supernatant hemoglobin and red blood cell ATP were also unaffected.