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Filtration Leukapheresis: The Influence of Granulocyte Counts Upon the Donors' Yield
Author(s) -
Kosmidis P. A.,
Lewandowski S.
Publication year - 1979
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1979.19479250187.x
Subject(s) - leukapheresis , granulocyte , filtration (mathematics) , medicine , yield (engineering) , premedication , volunteer , surgery , biology , mathematics , materials science , statistics , genetics , stem cell , cd34 , agronomy , metallurgy
The purpose of this investigation was to determine the influence of granulocyte count on the yield of granulocytes. Healthy adult volunteer donors underwent filtration leukapheresis without premedication. The granulocyte count was measured before and immediately after the procedure. In 73 donors, there was an increase and in 67 donors there was a decrease in the granulocyte counts. In this study of nonmedicated donors those with high initial granulocyte counts and those in which there was a large increase in the postleukapheresis granulocyte counts provided the best yield with the filtration leukapheresis technique.