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The Effect of Temperature Variations on Cryoprecipitate
Author(s) -
Rock G. A.,
Tittley P.
Publication year - 1979
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1979.19179160274.x
Subject(s) - cryoprecipitate , blood preservation , chemistry , zoology , chromatography , andrology , medicine , biology , biochemistry , fibrinogen
The effect of temperature on Factor VIII levels in blood and cryoprecipitate was assessed. Freshly collected units of blood required several hours to reach 4 C, but this delay seemed of little importance since equal amounts of cryoprecipitated Factor VIII were recovered from blood stored either at 22 C or at 4 C. Freezing at −80, −60, or −40 C produced identical yields of Factor VIII, whereas freezing at −20 C resulted in significantly lower recoveries. This might be expected if one considers the physiochemical changes that occur during the freezing process.