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Stability of Neutrophil‐Releasing Activity of Plasma Obtained from Leukapheresed Rats and Stored at 4 C
Author(s) -
Roy A. J.,
Ramirez M.,
Valeri C. R.
Publication year - 1978
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1978.18679077958.x
Subject(s) - granulocytosis , granulocyte , chemistry , neutrophile , endocrinology , medicine , immunology , biochemistry , in vitro
When granulocyte‐donor rats were treated prior to pheresis with plasma obtained from previously leukapheresed rats (PPP), granulocytosis and a significant increase in granulocyte yield were observed. Previous studies have demonstrated that such plasma stored at –150 C for up to two weeks preserved the neutrophil‐releasing activity. This study demonstrates that neutrophil‐releasing activity was satisfactorily preserved when plasma from previously leukapheresed rats was stored at 4 C for three weeks.