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Autoimmune Hemolytic Anemia with Anti Jk a Specificity in a Patient Taking Aldomet
Author(s) -
Patten E.,
Becki C. E.,
Scholl C.,
Stroope R. A.,
Wukasch C.
Publication year - 1977
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1977.17578014595.x
Subject(s) - autoimmune hemolytic anemia , hemolytic anemia , medicine , anemia , immunology
Autoimmune hemolytic anemia (hemoglobin 5.2 g, reticulocyte count 31.0 per cent) developed in a 53‐year‐old hypertensive woman who was taking Aldomet. Both the patient's serum and the eluate prepared from her red blood cells contained an antibody with anti‐Jk a specificity. Rapid sustained improvement in the anemia occurred after cessation of Aldomet and a two week course of prednisone therapy. Eight months later, anti‐Jk a was no longer detectable in the patient's serum and the direct antiglobulin test was nonreactive.