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Abdominal pain in donors during filtration leukapheresis
Author(s) -
Wiltbank TB,
Nusbacher J.,
Higby DJ,
MacPherson JL
Publication year - 1977
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1977.17277151922.x
Subject(s) - leukapheresis , medicine , filtration (mathematics) , abdominal pain , surgery , pathogenesis , anesthesia , biology , statistics , genetics , mathematics , stem cell , cd34
An unusual donor reaction characterized primarily by lower abdominal and/or perineal pain occurs in 1.2 per cent of donors during filtration leukapheresis (FL). The reaction occurs almost exclusively in female donors. Corticosteroid pretreatment appears to be highly effective in preventing the reaction. The pathogenesis of this donor problem is speculative.