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Factors Affecting the Efficiency of Filtration Leukapheresis
Author(s) -
Katz A. J.,
Houx J.,
Morse E. E.
Publication year - 1977
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1977.17177128890.x
Subject(s) - leukapheresis , filtration (mathematics) , dexamethasone , volunteer , granulocyte , medicine , yield (engineering) , biology , mathematics , statistics , genetics , materials science , stem cell , cd34 , agronomy , metallurgy
Continuous flow filtration leukapheresis was performed on normal volunteer donors with and without intravenous administration of dexamethasone. Although granulocyte counts were increased in steroid treated donors and almost 20 per cent more cells were presented to the filters, the final yield of granulocytes was slightly decreased and the efficiency of collection during a two‐ to three‐hour leukapheresis was statistically significantly decreased.