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Rapid in Vivo Destruction of Yt(a+) Erythrocytes in a Recipient with Anti‐Yt a
Author(s) -
Ballas S. K.,
Sherwood W. C.
Publication year - 1977
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1977.17177128889.x
Subject(s) - antibody , titer , in vivo , red blood cell , red cell , immunology , blood transfusion , medicine , andrology , biology , genetics
A patient with anti‐Cartwright (anti‐Yt a ) is reported. Immunohematologic studies showed this antibody to be an IgG immunoglobulin that does not bind complement. A 51 Cr red blood cell survival study resulted in a greatly reduced half‐life of less than six hours of Yt(a+) cells. The antibody titer increased threefold after the red blood cell survival study. Determination of red cell survival is indicated when crossmatch‐incompatible blood transfusion is considered.