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The Uptake and Egress of Adenine from Human Red Blood Cells in Vitro
Author(s) -
Moore G. L.,
Ledford M. E.
Publication year - 1977
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1977.17177128882.x
Subject(s) - in vitro , red blood cell , chemistry , human blood , red cell , dilution , human plasma , plasma , blood plasma , biochemistry , chromatography , biology , medicine , physiology , thermodynamics , physics , quantum mechanics
The initial uptake of adenine from plasma by human red blood cells was measured at 0,10, and 20C. Initial uptake is completed in several minutes as distribution equilibrium is reached; however, total uptake requires several weeks at 4C. Adenine inside the red blood cell was shown to egress to the plasma if the equilibrium shifted due to plasma dilution or exchange.