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A pH‐Dependent Auto‐agglutinin with Anti‐P Specificity
Author(s) -
Judd W. J.
Publication year - 1975
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1975.15476034562.x
Subject(s) - agglutinin , cold agglutinin disease , membrane , red blood cell , cold agglutinin , receptor , chemistry , biochemistry , antibody , immunology , biology , lectin , autoantibody
An agglutinin with apparent anti‐P specificity, reactive only at pH values below 6.0, was found in the plasma of a healthy female blood donor. It is postulated that this agglutinin recognizes latent receptors revealed by structural alterations to red blood cell membranes which occur in an acid environment.