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Mixed‐Field Polyagglutinability Due to Tn: A Further Example
Author(s) -
Moore B. P. L.,
Marsh S.,
Laschinger C.,
Simpson S.
Publication year - 1975
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1046/j.1537-2995.1975.15175103511.x
Subject(s) - papain , arachis hypogaea , salvia , biology , traditional medicine , microbiology and biotechnology , botany , immunology , medicine , biochemistry , enzyme
Mixed‐field polyagglutination of red blood cells caused by the presence of the determinant Tn can be distinguished from other causes of polyagglutination such as T and Cad [Sd(a ++)] by tests with four plant hemagglutinins— Doliches biflorus, Arachis hypogaea, Salvia sclarea , and Salvia horminum. Inhibition of the reactions of Tn cells with Dolichos biflorus and Salvia horminum when the cells are pretreated with papain and negative reactions of Tn cells with sera from other known cases lend support to the diagnosis.