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Hysterectomy, Oophorectomy, and Cognitive Function in Older Women
Author(s) -
KritzSilverstein Donna,
BarrettConnor Elizabeth
Publication year - 2002
Publication title -
journal of the american geriatrics society
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.992
H-Index - 232
eISSN - 1532-5415
pISSN - 0002-8614
DOI - 10.1046/j.1532-5415.2002.50008.x
Subject(s) - oophorectomy , medicine , hysterectomy , estrogen , menopause , gynecology , hormone replacement therapy (female to male) , obstetrics , testosterone (patch) , surgery
It has been proposed that estrogen deficiency is a cause of memory loss in postmenopausal women. Bilateral oophorectomy leads to an abrupt decrease in gonadal hormone levels including testosterone. Hysterectomy with ovarian conservation may also lead to a decline in ovarian hormones. This study examines the effects of hysterectomy and oophorectomy on cognitive function in a large sample of older, postmenopausal women with and without current estrogen replacement therapy.