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Abstracts of the 8th Meeting of the Italian Peripheral Nerve Study Group: 26
Author(s) -
Conti V,
Padua L,
Caliandro P,
Aprile I,
Pazzaglia C,
Tonali P
Publication year - 2003
Publication title -
journal of the peripheral nervous system
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1
H-Index - 67
eISSN - 1529-8027
pISSN - 1085-9489
DOI - 10.1046/j.1529-8027.2003.00026.x
Subject(s) - medicine , ulnar nerve , elbow , ulnar neuropathy , entrapment neuropathy , peripheral neuropathy , nerve conduction velocity , surgery , nerve conduction , nerve conduction study , anatomy , carpal tunnel syndrome , endocrinology , diabetes mellitus
To our knowledge there are no evidence of other multientrapment neuropathy related to growth hormone (GH) administration. We observed the case of a 45 year‐old bodybuilder complaining of paraesthesias and dysaesthesias in hands and feet after self‐administration of high‐dose of recombinant GH therapy. The patient complained of these transitory symptoms after each cycle of GH therapy. Electrodiagnostic studies showed: 1)“moderate” right CTS and “minimal” left CTS; 2)“mild” right ulnar entrapment at elbow; 3) decrease in left ulnar motor nerve conduction in the segment across the elbow; 4) decrease in left ulnar sensory nerve action potential amplitude; and 5) bilateral absence of ulnar nerve F‐wave from abductor digiti minimi. Our data suggested multiple nerve entrapment at upper limbs. Moreover, basing on the history of feet paraesthesia, we hypothesized a mild involvement of distal sensory fibers in the legs, which was not assessed by neurophysiological studies. The anecdotal history and neurophysiological findings of this case suggest that more attention should be paid to the adverse effects of GH on peripheral nerves.