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Blistering disorders: diagnosis and treatment
Author(s) -
Yeh S. W.,
Ahmed Babar,
Sami Naveed,
Ahmed A. Razzaque
Publication year - 2003
Publication title -
dermatologic therapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.595
H-Index - 68
eISSN - 1529-8019
pISSN - 1396-0296
DOI - 10.1046/j.1529-8019.2003.01631.x
Subject(s) - medicine , dermatitis herpetiformis , dermatology , bullous pemphigoid , epidermolysis bullosa acquisita , pemphigus vulgaris , pemphigus , porphyria cutanea tarda , cicatricial pemphigoid , epidermolysis bullosa , paraneoplastic pemphigus , pemphigoid , immunopathology , disease , pathology , autoantibody , immunology , antibody
Blistering diseases are a heterogeneous group of disorders that can affect either skin and mucous membrane, or both, varying in presentation, clinical course, pathohistology, immunopathology and treatment. Not infrequently the diagnosis is delayed. This can result in severe, and sometimes fatal consequences. Although these diseases are rare, it is very important to make an accurate diagnosis based on a combination of clinical profile and laboratory observations. A brief review is presented of the following bullous diseases: pemphigus, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, epidermolysis bullosa acquisita, dermatitis herpetiformis, linear IgA bullous disease, porphyria cutanea tarda, and subcorneal pustular dermatitis. Their clinical, pathohistologic and immunopathologic features and recommendations for therapy are discussed.