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Diffusion‐weighted Imaging Abnormalities in the Splenium after Seizures
Author(s) -
Oster Joel,
Doherty Colin,
Grant P. Ellen,
Simon Mirela,
Cole Andrew J.
Publication year - 2003
Publication title -
epilepsia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.687
H-Index - 191
eISSN - 1528-1167
pISSN - 0013-9580
DOI - 10.1046/j.1528-1157.2003.40902.x
Subject(s) - splenium , corpus callosum , epilepsy , white matter , diffusion mri , anticonvulsant , medicine , neuroscience , anesthesia , psychology , magnetic resonance imaging , pathology , radiology
Summary: Purpose: Transient increased T 2 signal in the splenium of the corpus callosum after seizures has been reported and sometimes attributed to a postulated toxicity of anticonvulsant medications (AEDs). Methods: We describe two patients with bitemporal epilepsy. Results: Transiently increased T 2 signal (in one) and decreased apparent diffusion coefficient (ADC) (in both) in the splenium appeared to be related directly to acute seizures. Conclusions: These cases illustrate an unusual acute postictal imaging finding, highlight involvement of an important commissural pathway, and suggest that seizures per se, and not their treatment, are the cause of transient white‐matter abnormalities in these cases.