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Prevalence of Atrial Septal Aneurysm in Patients With Migraine: An Echocardiographic Study
Author(s) -
Carerj S.,
Narbone M. C.,
Zito C.,
Serra S.,
Coglitore S.,
Pugliatti P.,
Luzza F.,
Arrigo F.,
Oreto G.
Publication year - 2003
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1046/j.1526-4610.2003.03129.x
Subject(s) - migraine , medicine , aura , cardiology , migraine with aura , aneurysm , stroke (engine) , transthoracic echocardiogram , surgery , mechanical engineering , engineering
Objective.—To evaluate the prevalence of atrial septal aneurysm in patients with migraine. Background.—Migraine has long been considered a risk factor for stroke. Atrial septal aneurysm is often observed in young patients with ischemic stroke and is frequently associated with other conditions potentially leading to embolism. Methods.—We performed a transthoracic echocardiogram in 90 consecutive patients (65 women and 25 men; mean age, 35.3 years [standard deviation, 9]) with migraine but free from cerebral and cardiovascular disease and in 53 control subjects (37 women and 16 men; mean age, 34 years [standard deviation, 10]). The diagnosis of atrial septal aneurysm was performed according to Olivares‐Reyes criteria. A transesophageal echocardiogram also was performed in 75 patients with migraine (83.3%). Results.—The prevalence of isolated atrial septal aneurysm was higher in patients with migraine with aura (28.5%) than in patients with migraine without aura (3.6%) ( P < .005) or in control subjects (1.9%) ( P < .005) . Conclusions.—Our data suggest a role of atrial septal aneurysm in the genesis of aura in patients with migraine.