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Sensitization of trigeminal nociception specific for migraine but not pain of sinusitis.
Author(s) -
Katsarava Z,
Lehnerdt G,
Duda B,
Ellrich J,
Diener HC,
Kaube H
Publication year - 2003
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1046/j.1526-4610.2003.03085_8.x
Subject(s) - migraine , nociception , medicine , trigeminal nerve , anesthesia , sinusitis , neurology , nociceptor , corneal reflex , facilitation , central sensitization , neuroscience , reflex , psychology , surgery , psychiatry , receptor
Neurology. 2002;59:1450‐1453. Trigeminal pain processing was studied in 14 patients with unilateral migraine attacks and 14 age‐ and sex‐matched patients with comparable unilateral headache from frontal sinusitis. Using a nociception‐specific blink reflex method (nBR), a facilitation of nBR responses predominantly on the headache side was observed in migraine, but not in sinusitis. The facilitation of trigeminal nociception may be specific for migraine rather than a consequence of peripheral pain such as frontal sinusitis. Comment: Here we have evidence for the central hyperexcitability of migraine, not found in the previously cited article by Boska et al. SJT