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Intravenous Propofol in the Treatment of Refractory Headache
Author(s) -
Mendes Paula M.,
Silberstein Stephen D.,
Young William B.,
Rozen Todd D.,
Paolone Mary F.
Publication year - 2002
Publication title -
headache: the journal of head and face pain
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.14
H-Index - 119
eISSN - 1526-4610
pISSN - 0017-8748
DOI - 10.1046/j.1526-4610.2002.02151.x
Subject(s) - propofol , medicine , refractory (planetary science) , headaches , anesthesia , surgery , physics , astrobiology
We analyzed the results of treating patients who had chronic daily headaches that were refractory to standard medications with repetitive low‐dose boluses of intravenous propofol (2,6‐diisopropylphenol). Patients were treated over a 1‐year period at Thomas Jefferson University Hospital. A total of 18 patients were treated a total of 21 times. Over 90% of patients had at least some headache relief after treatment. The headache cycle was broken in eight patients. There were no complications. Intravenous propofol is safe and effective when used under monitored conditions and should be considered for patients who have refractory chronic daily headache and have failed other interventions.