Premium
Extracorporal Low‐density Lipoprotein Elimination by Immunoadsorption
Author(s) -
Ritter M.M.,
Parhofer K.G.
Publication year - 2003
Publication title -
therapeutic apheresis and dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.415
H-Index - 53
eISSN - 1744-9987
pISSN - 1744-9979
DOI - 10.1046/j.1526-0968.2003.00054.x
Subject(s) - immunoadsorption , apheresis , medicine , ldl apheresis , coronary heart disease , cholesterol , lipoprotein , intensive care medicine , cardiology , immunology , antibody , platelet
Low‐density lipoprotein (LDL) apheresis has proven its therapeutic usefulness in patients who suffer from coronary heart disease but cannot achieve LDL cholesterol concentrations defined by the National Cholesterol Education Program guidelines. Immunoadsorption was the first commercially available apheresis technique. It is based on affinity chromatography. As with other apheresis techniques, immunoadsorption has specific advantages and disadvantages. These have to be taken into account when selecting an apheresis technique for the individual patient.