Premium
Design Progress of the Ultracompact Integrated Heart Lung Assist Device—Part 1: Effect of Vaned Diffusers on Gas‐Transfer Performances
Author(s) -
Tsukiya Tomonori,
Tatsumi Eisuke,
Nishinaka Tomohiro,
Katagiri Nobumasa,
Takewa Yoshiaki,
Ohnishi Hiroyuki,
Oshikawa Mitsuo,
Shioya Kyoko,
Mizuno Toshihide,
Taenaka Yoshiyuki,
Takano Hisateru,
Kitamura Soichiro
Publication year - 2003
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.2003.00024.x
Subject(s) - impeller , materials science , diffuser (optics) , hemolysis , injector , extracorporeal membrane oxygenation , coaxial , biomedical engineering , mechanical engineering , engineering , surgery , medicine , optics , light source , physics , immunology
The integrated heart lung assist device (IHLAD) has been developed to overcome the problems of currently available extracorporeal membrane oxygenation devices. The integrated structure of a centrifugal blood pump and cylindrical bundle of polyolefin hollow‐fibers has allowed a remarkably compact size for the device. This study deals with the design change of the IHLAD that added to the vaned diffuser between the impeller of the centrifugal pump and the hollow‐fiber bundle with a view to enhancing the gas‐transfer performance. Ex vivo gas‐transfer performance tests were carried out, as well as hydrodynamic characteristics and hemolysis test using fresh goat blood. The oxygen transfer rate was generally improved, and the carbon dioxide removal rate was slightly improved. Intolerable amount of hemolysis (index of hemolysis= 0.177) was caused by the IHLAD, which must be resolved by improving the design in the future.