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A Honeycomb Collagen Carrier for Cell Culture as a Tissue Engineering Scaffold
Author(s) -
Itoh Hiroshi,
Aso Yu,
Furuse Masayasu,
Noishiki Yasuharu,
Miyata Teruo
Publication year - 2001
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.2001.025003213.x
Subject(s) - scaffold , honeycomb , tissue engineering , cell culture , materials science , biomedical engineering , honeycomb structure , chemistry , biophysics , composite material , engineering , biology , genetics
Abstract: As a three‐dimensional carrier for cell culture, a honeycomb structure cell scaffold was created from atelopeptide collagen Types I, II, and III. The diameter of the honeycomb pores ranged from 100 to 1,000 μm. The depth of the pores was from 10 to 3,000 mm. The scaffold was elastic and hard. Creation of various shapes was easy, and these shapes were easily maintained. Human fibroblasts, CHO‐K1, BHK‐21, and bovine endothelial cells were cultured with the scaffold. The growth curves of these cells were satisfactory. These results suggest that this carrier is a suitable scaffold for cell culture and will be useful as a three‐dimensional tissue engineering scaffold.