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Analysis of the Arterial Blood Pressure Waveform During Left Ventricular Nonpulsatile Assistance in Animal Models
Author(s) -
Kawahito Shinji,
Takano Tamaki,
Nakata Kinichi,
Maeda Tomohiro,
aka Kenji,
Linneweber Joerg,
SchulteEistrup Sebastian,
Sato Tsutomu,
Mikami Minoru,
Glueck Julie,
Nosé Yukihiko
Publication year - 2000
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.2000.06646.x
Subject(s) - blood pressure , waveform , medicine , cardiology , ventricular assist device , pulsatility index , pulse pressure , oscilloscope , biomedical engineering , heart failure , computer science , biology , telecommunications , radar , detector , pregnancy , fetus , genetics
When the rotary blood pump is used as a left ventricular assist device (LVAD), the arterial blood pressure waveform changes with the LVAD condition. Based on evidence from an in vitro study, the change of the arterial blood pressure waveform during left ventricular assistance was evaluated using animal models. After the left pleural cavity was opened through the fifth intercostal space under general anesthesia, a rotary blood pump was implanted as an LVAD into 6 healthy calves. The direct left carotid arterial blood pressure waveform was measured and recorded by an oscilloscope. The Fast Fourier Transform technique was utilized to analyze the arterial blood pressure waveform and calculate the pulsatility index (PI) and the pulse power index (PPI). Similar to the in vitro study, the PI and PPI decreased exponentially with the increase of the LVAD assist ratio. By using this analysis methodology, a physiologically effective ventricular assistance might be achieved.