Premium
In Vitro Evaluation Study of the Membrane Autotransfusion System Experimental Prototype: MATS–I
Author(s) -
Fukunaga Ken,
Shimoyama Takashi,
Sawada Koji,
Mueller Juergen,
Sueoka Akinori,
Nosé Yukihiko
Publication year - 2000
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.2000.06428.x
Subject(s) - autotransfusion , hematocrit , membrane , biomedical engineering , hollow fiber membrane , chromatography , materials science , surgery , chemistry , medicine , blood transfusion , biochemistry
Membrane Autotransfusion System (MATS) utilizing plasmapheresis technology has been developed in our laboratory. A specially designed polyethylene hollow fiber membrane was utilized. This study was conducted to evaluate performance of the first experimental prototype, MATS‐I. The results of this study showed that the MATS‐I could concentrate diluted blood at 10% of the initial hematocrit concentration (HCTi) into over 40% after passing through the system at a transmembrane pressure of 70 mm Hg. Moreover, the MATS‐I can continuously treat 10,000 ml of diluted blood at various HCTi levels without deteriorating its performances. Even though the MATS‐I met all required performances as an autotransfusion system, several areas of improvement of the system were necessary to meet various clinical needs. The next prototype, MATS‐II, can be designed based on experiences obtained from the MATS‐I. The MATS is smaller, more atraumatic and continuous, and is a faster system when compared to the currently available centrifugal autotransfusion devices.