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Cardiac Autonomic Nervous Function During Long‐Term Nonpulsatile Left Heart Bypass
Author(s) -
Nishinaka Tomohiro,
Tatsumi Eisuke,
Nishimura Takashi,
Taenaka Yoshiyuki,
Masuzawa Toru,
Nakata Masako,
Takano Hisateru,
Koyanagi Hitoshi
Publication year - 1999
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.1999.06390.x
Subject(s) - pulsatile flow , autonomic nervous system , cardiology , medicine , heart rate variability , heart rate , sympathetic nervous system , blood pressure
We investigated the changes in cardiac autonomic nervous activities during long‐term nonpulsatile left heart bypass (NLHB) by analyzing heart rate variability. A pulsatile ventricular assist device was installed in 3 goats, and pulsatile left heart bypass (PLHB) was conducted for 2 weeks. Then, NLHB was maintained for the following 4 weeks. The segmental data of the R‐R intervals (R‐Rs) was analyzed by maximum entropy spectral analysis. Changes in evaluated parameters from the last week of PLHB to the 4th week of NLHB were as follows: the mean R‐Rs increased from 511 ms to 692 ms; the coefficient of variation of R‐R increased from 10.2 to 14.1%; the power of the low frequency band (LF) increased from 747 ms 2 to 2,855 ms 2 ; the power of the high frequency band (HF) increased from 512 ms 2 to 1,270 ms 2 ; and the ratio of LF to HF increased from 2.6 to 6.5. These results indicated that the cardiac autonomic nervous activity, both sympathetic and parasympathetic, increased during long‐term NLHB.