Premium
Peritoneal Clearance and Peritoneal Transfer of Oxalic Acid, Vitamin C, and Vitamin B 6 During Continuous Ambulatory Peritoneal Dialysis
Author(s) -
M Mydlík,
K Derzsiová,
J Svác,
P Dlhopolcek,
E Zemberová
Publication year - 1998
Publication title -
artificial organs
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.684
H-Index - 76
eISSN - 1525-1594
pISSN - 0160-564X
DOI - 10.1046/j.1525-1594.1998.06220.x
Subject(s) - oxalic acid , peritoneal dialysis , continuous ambulatory peritoneal dialysis , vitamin , chemistry , medicine , endocrinology , biochemistry
The peritoneal clearance and peritoneal transfer of oxalic acid, vitamin C, and vitamin B 6 in 32 patients during continuous ambulatory peritoneal dialysis (CAPD) using peritoneal dialysis solutions containing 1.5% or 2.5% glucose were examined. The plasma level of oxalic acid was significantly elevated in all patients, plasma vitamin C was in the normal range or in the upper margin of the normal range, and plasma vitamin B 6 was in the normal range. The peritoneal clearance of oxalic acid was significantly lower, and the peritoneal clearance of vitamin B 6 was the lowest in comparison to the peritoneal clearance of urea. With the exception of vitamin B 6 , the peritoneal clearance and peritoneal transfer of the examined parameters increased using the dialysis solution containing 2.5% glucose. We found direct relationships between the plasma levels of oxalic acid and creatinine as well as plasma vitamin C and between the peritoneal transfer of oxalic acid and the peritoneal transfer of vitamin C as well as vitamin B 6 . The significant hyperoxalemia of our patients was found to persist despite the relatively high peritoneal transfer of oxalic acid during CAPD. These results suggest that CAPD is not a method effective enough for permanent reduction of the plasma levels of oxalic acid.