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Imiquimod is Highly Effective for Extensive, Hyperproliferative Condyloma in Children
Author(s) -
Majewski Slawomir,
Pniewski Tomasz,
Malejczyk Magdalena,
Jablonska Stefania
Publication year - 2003
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2003.20516.x
Subject(s) - imiquimod , medicine , dermatology , human papillomavirus , girl , psychology , developmental psychology
We describe a dramatic response to imiquimod of long‐lasting, highly proliferative extensive perianal condylomas involving the anal canal in a 19‐month‐old girl. Her mother was free of condyloma and allegedly had no human papillomavirus (HPV) infection during pregnancy. There was no evidence of sexual abuse. Application of 5% imiquimod cream to the child every other day for 3 weeks resulted in almost complete resolution of the warts, with total clearance within another 2 weeks. The inflammatory reaction was moderate. Since there is still discussion of whether imiquimod may be prescribed for small children, this case of very extensive condyloma provides evidence that the compound is safe and highly effective.