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Gangrenous Cutaneous Mucormycosis in a Child with a Solid Organ Transplant: A Case Report and Review of the Literature
Author(s) -
Boyd Alan S.,
Wiser Britt,
Sams Hunter H.,
King Lloyd E.
Publication year - 2003
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2003.20508.x
Subject(s) - medicine , immunosuppression , solid organ , bone marrow transplant , mucormycosis , organ transplantation , presentation (obstetrics) , population , cellulitis , bone marrow transplantation , intensive care medicine , transplantation , surgery , immunology , environmental health
Infections by members of the Phycomycetes class of fungi typically arise in patients with substantial underlying immunosuppression. Several clinical presentations, including that of gangrenous cellulitis, have been described. In the pediatric population, critically ill premature newborns and older children with underlying hematopoietic malignancies and/or bone marrow transplantation are affected. Presentation in children with solid organ transplants is rare. Successful therapy for this condition includes aggressive debridement of infected tissue and systemic administration of amphotericin B.