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A Pediatric Case of Sclerodermatous Chronic Graft‐versus‐Host Disease
Author(s) -
Terasaki Kenjiro,
Kanekura Takuro,
Setoyama Mitsuru,
Kanzaki Tamotsu
Publication year - 2003
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2003.20411.x
Subject(s) - medicine , graft versus host disease , scleroderma (fungus) , bone marrow transplantation , disease , aplastic anemia , pathogenesis , graft vs host reaction , transplantation , anemia , immunology , bone marrow , pathology , surgery , inoculation
We report a rare case of sclerodermatous chronic graft‐versus‐host disease (GVHD) in a 6‐year‐old boy that occurred after bone marrow transplantation for his aplastic anemia. The clinical manifestation and histopathologic findings were typical of scleroderma. Although various kinds of treatment have been tried for scleroderma, no established therapy exists. Furthermore, treating this disease is even more difficult in children. In the future, clarification of the pathogenesis of chronic GVHD and establishment of therapy will be necessary.