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Granular Parakeratosis in Children: Case Report and Review of the Literature
Author(s) -
Pimentel Dalva Regieto,
Michalany Nilceo,
Morgado de Abreu Marilda Aparecida Milanêz,
Petlik Beno,
Alchorne Maurício Mota de Avelar
Publication year - 2003
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2003.20306.x
Subject(s) - intertriginous , parakeratosis , dermatology , medicine , etiology , dyskeratosis , rash , presentation (obstetrics) , hyperkeratosis , disease , pathology , surgery
Granular parakeratosis is a cutaneous eruption with erythematous and/or brownish hyperkeratotic papules and plaques which are exclusively localized to intertriginous areas and show histopathologic features of an unusual form of parakeratosis. The etiology is unknown, but the excessive use of various topical preparations (e.g., ointments and deodorants) has been associated with this disease. It has heretofore been reported only in adults. We report two children, ages 3 and 5 months, with characteristic lesions in the groin associated with topical pomades used to prevent diaper rash. This is the first report associating the clinical presentation and the histopathologic diagnosis of granular parakeratosis in children. The literature on this entity is also reviewed and all case reports are summarized.