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Pyoderma Gangrenosum in Two Siblings: A Familial Predisposition
Author(s) -
Khandpur Sujay,
Mehta Surjit,
Nagi Reddy Belum Siva
Publication year - 2001
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2001.01936.x
Subject(s) - pyoderma gangrenosum , medicine , dapsone , dermatology , pediatrics , surgery , disease
We report pyoderma gangrenosum in two siblings with onset during childhood and no associated systemic abnormalities. The patients were born of nonconsanguineous, healthy parents. Treatment with oral corticosteroids produced an excellent clinical response, followed by recurrence after cessation of therapy. Steroids were restarted in combination with dapsone to prevent further recurrence.