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Giant Congenital Melanocytic Nevus with Underlying Hypoplasia of the Subcutaneous Fat
Author(s) -
Caradona Stephanie A.,
Skidmore Robert,
Gupta Anu,
Bush Charles H.,
Ford Michael J.
Publication year - 2000
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.2000.017005387.x
Subject(s) - medicine , hypoplasia , congenital melanocytic nevus , magnetic resonance imaging , nevus , anatomy , radiology , melanoma , cancer research
A 17‐week‐old boy with a giant congenital melanocytic nevus (GCMN) of the left lower extremity was noted to have a reduction in circumference of the left lower extremity relative to the contralateral side. The skin overlying the GCMN was persistently warm when compared with the surrounding and contralateral skin. Comparative plain radiography, ultrasonography, and magnetic resonance imaging showed fat hypoplasia of the left lower extremity, with bone and muscle appearing unaffected. The possible role of cytokines produced by the nevus in fat hypoplasia in GCMN is discussed.