Premium
Childhood Immunobullous Disease Following a Second Organ Transplant
Author(s) -
Morelli Joseph G.,
Weston William L.
Publication year - 1999
Publication title -
pediatric dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.542
H-Index - 73
eISSN - 1525-1470
pISSN - 0736-8046
DOI - 10.1046/j.1525-1470.1999.00033.x
Subject(s) - medicine , pemphigus , dermatology , organ transplantation , pemphigoid , disease , bullous pemphigoid , transplantation , immunology , pathology , surgery , antibody
Immunobullous diseases are quite unusual in children. We report two children who developed immunobullous disease shortly after a second solid organ transplantation. One child had IgA pemphigus vegetans, the other bullous pemphigoid. We hypothesize that the repeat organ transplantation served as a “booster” immunization for autoantibody production. Both children developed their immunobullous condition while being treated with immunosuppressive drugs that are used to treat immunobullous disorders.