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Fellows' Forum in Dialysis
edited by Mark A. Perazella: Cardiac Troponins: Utility in Renal Insufficiency and End‐Stage Renal Disease
Author(s) -
Watnick Suzanne,
Perazella Mark A.
Publication year - 2002
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1046/j.1525-139x.2002.00090.x
Subject(s) - medicine , myocardial infarction , cardiology , troponin , dialysis , end stage renal disease , cardiac marker , acute coronary syndrome , troponin complex , disease , population , troponin i , intensive care medicine , environmental health
Currently available serum markers of cardiac injury in patients with renal insufficiency suffer from impaired sensitivity and specificity. Cardiac troponins (cTnI, cTnT) are relatively new diagnostic markers of myocardial injury and have gained widespread application in the non‐renal‐failure population to diagnose myocardial infarction. Over the past few years the specificity and sensitivity of cardiac troponins for diagnosing acute myocardial infarction in patients with renal dysfunction have been examined. Most data indicate that cardiac troponin I has an excellent specificity, but until more studies are available this marker should be consdiered a useful but imperfect serum marker of an acute coronary syndrome in patients with underlying renal dysfunction.