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Reconsidering the Importance of Long‐Term Low‐Level Aluminum Exposure in Renal Failure Patients
Author(s) -
CannataAndía Jorge B.
Publication year - 2001
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1046/j.1525-139x.2001.00002.x
Subject(s) - medicine , aluminium , toxicity , renal osteodystrophy , chronic renal failure , intensive care medicine , kidney disease , metallurgy , materials science
Aluminum toxicity is widely considered a problem of the past. However, low‐level aluminum exposure and low but abnormal body burdens of aluminum are common. Aluminon, the routinely used histochemical stain for aluminum in bone, has a low sensitivity. The role of aluminum in renal osteodystrophy needs to be reassessed using more sensitive techniques. Low‐level aluminum exposure also may result in subtle neurological dysfunction, another area that needs further investigation.