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ACID‐BASE IN RENAL FAILURE: A Review of the Effects of Correction of Acidosis on Nutrition in Dialysis Patients
Author(s) -
Brady John P.,
Hasbargen James A.
Publication year - 2000
Publication title -
seminars in dialysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.899
H-Index - 78
eISSN - 1525-139X
pISSN - 0894-0959
DOI - 10.1046/j.1525-139x.2000.00068.x
Subject(s) - medicine , metabolic acidosis , acidosis , dialysis , renal tubular acidosis , hemodialysis , cardiology , endocrinology , intensive care medicine
Metabolic acidosis is a condition that is commonly encountered in both chronic renal failure (CRF) and in end‐stage renal disease (ESRD). Known complications and surmised consequences associated with the acidosis of renal disease include bone lesions, depression of myocardial contractility, and growth retardation. Conversely the correction of acidosis in children with renal tubular acidosis improves growth velocity. This is also the case in children with CRF. The conclusion drawn from this study was that the correction of metabolic acidosis improved serum albumin concentrations in patients on hemodialysis and that this correction also induced a decrease in the nPCR.