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Models for use in wound healing research: A survey focusing on in vitro and in vivo adult soft tissue
Author(s) -
Gottrup Finn,
Ågren Magnus S,
Karlsmark Tonny
Publication year - 2000
Publication title -
wound repair and regeneration
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.847
H-Index - 109
eISSN - 1524-475X
pISSN - 1067-1927
DOI - 10.1046/j.1524-475x.2000.00083.x
Subject(s) - wound healing , in vivo , soft tissue , medicine , variety (cybernetics) , computer science , pathology , surgery , biology , artificial intelligence , microbiology and biotechnology
Many different factors must be considered before selecting a wound healing model to use for a specific study. A wide variety of models have been developed that examine different aspects of the repair response, both in vitro and in vivo. In this review article, we focus on those systems that are most widely used for studies on adult soft tissue healing. Advantages and disadvantages of each are discussed, along with relevant background information to help guide decision‐making.