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Diagnosis of Helicobacter pylori infection
Author(s) -
Rautelin Hilpi,
Lehours Philippe,
Mégraud Francis
Publication year - 2003
Publication title -
helicobacter
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.206
H-Index - 79
eISSN - 1523-5378
pISSN - 1083-4389
DOI - 10.1046/j.1523-5378.2003.00168.x
Subject(s) - helicobacter pylori , serology , urea breath test , virulence , multiplex , multiplex polymerase chain reaction , medicine , helicobacter pylori infection , immunology , microbiology and biotechnology , biology , antibody , polymerase chain reaction , bioinformatics , genetics , gene
Numerous studies are still published on diagnostic tests for Helicobacter pylori , essentially for noninvasive tests. The urea breath test is applied in different types of patients, and there are attempts to have quicker and simpler protocols. Stool tests using monoclonal antibodies are now evaluated while serology is still a subject of interest. The progress in PCR (multiplex PCR, real‐time PCR) has also stimulated the research in this area of invasive tests, in order to get insight into virulence factors, macrolide susceptibility and to detect H. pylori in nonconventional specimens.