Premium
Ability of frequency doubling perimetry and scanning laser polarimetry to detect ocular hypertension and POAG in an Indian population
Author(s) -
Sukumar S.,
Balekuduru S.,
Mani B.,
Vijaya L.
Publication year - 2002
Publication title -
ophthalmic and physiological optics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.147
H-Index - 66
eISSN - 1475-1313
pISSN - 0275-5408
DOI - 10.1046/j.1475-1313.2002.00086_26.x
Subject(s) - scanning laser polarimetry , ophthalmology , ocular hypertension , medicine , glaucoma , visual field , open angle glaucoma , population , optometry , environmental health , nerve fiber layer
Purpose: To evaluate the ability of Frequency doubling perimetry (FDP) and scanning laser polarimetry (GDx) in the detection of Ocular hypertension (OHT) and Primary Open Angle Glaucoma (POAG) in an Indian population. Methods: Subjects were classified as being normal or having OHT or POAG (mild, moderate and severe) based on clinical findings and visual field results. A total of 104 eyes of 86 subjects who satisfied the inclusion criteria and completed the tests successfully were analysed. Sensitivity and specificity of N‐30 Full field FDP tests were analysed for OHT and three POAG groups. GDx parameters were compared between normal subjects and other groups. Results: When compared with normal subjects, superior‐based GDx parameters were significantly different ( p < 0.05) in OHT and mild POAG. Average‐based parameters showed significant difference ( p < 0.05) only in moderate and severe POAG. Among all the GDx parameters ‘The number’ (cut off value >19) showed significant results in OHT (sensitivity 66% and specificity 92%) and in POAG groups (sensitivity ≥88% and specificity ≥92%). OHT changes were detected by N 30 Full Threshold FDP test (sensitivity 22% and specificity 83%) and in mild (sensitivity 59% and specificity 87%), moderate (sensitivity 88% and specificity 96%) and severe (sensitivity 100% and specificity 100%) POAG groups when mean deviation ( P < 5) was used as the cut off value. Conclusion: Both FDP and GDx are valid screening tools for detecting OHT and POAG. The ability of GDx in detecting OHT and POAG improved if normal subjects from the Indian population are used for comparison.