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Effect of Eurycoma longifolia Jack on orientation activities in middle‐aged male rats
Author(s) -
Ang H. H.,
Lee K. L.
Publication year - 2002
Publication title -
fundamental and clinical pharmacology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.655
H-Index - 73
eISSN - 1472-8206
pISSN - 0767-3981
DOI - 10.1046/j.1472-8206.2002.00106.x
Subject(s) - licking , sniffing , climbing , adult male , orientation (vector space) , physiology , biology , medicine , anatomy , endocrinology , ecology , geometry , mathematics
The effects of various fractions of Eurycoma longifolia Jack were studied on the orientation activities of the inbred, adult middle‐aged Sprague–Dawley rats, 9 months old and retired breeders towards the receptive females (anogenital sniffing, licking, mounting), the environment (climbing, raring, exploration), themselves (nongenital grooming, genital grooming) and mobility (restricted, unrestricted) after treating these subjects twice daily for 10 days. Results showed that subjects treated with 800 mg/kg of E. longifolia Jack increased orientation activities towards the receptive females (anogenital sniffing, licking and mounting), increased genital grooming towards themselves and restricted movements to a particular area of the cage but decreased interest in the external environment (climbing, raring, exploration) as compared with the controls during the investigation period. In conclusion, this study gives further evidences that different fractions of E. longifolia Jack modified the orientation activities of the middle‐aged male rats.