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Adhesion of inactivated probiotic strains to intestinal mucus
Author(s) -
Ouwehand A.C.,
Tölkkö S.,
Kulmala J.,
Salminen S.,
Salminen E.
Publication year - 2000
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1472-765x.2000.00773.x
Subject(s) - probiotic , mucus , lactobacillus casei , microbiology and biotechnology , propionibacterium freudenreichii , adhesion , bacteria , lactobacillus , biology , lactobacillaceae , chemistry , food science , ecology , genetics , organic chemistry
It has been suggested that probiotics should be viable in order to elicit beneficial health effects. Inactivation of probiotics has been suggested to interfere with the binding to the mucosa and thereby with the immune modulating activity of probiotics. The effect of different inactivation methods on the mucus adhesion of nine probiotic strains was studied. Inactivation by heat or γ‐irradiation generally decreased the adhesive abilities. However, heat treatment increased the adhesion of Propionibacterium freudenreichii and γ‐irradiation enhanced the adhesion of Lactobacillus casei Shirota. Inactivation by u.v. was not observed to modulate the adhesion of the tested strains and it was concluded to be the most appropriate method for studying non‐viable probiotics and preparing control products.