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Anti‐adhesive activity of sulphated exopolysaccharides of microalgae on attachment of red sore disease‐associated bacteria and Helicobacter pylori to tissue culture cells
Author(s) -
GuzmanMurillo M.A.,
Ascencio F.
Publication year - 2000
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1472-765x.2000.00751.x
Subject(s) - microbiology and biotechnology , biology , glycoconjugate , pathogen , staphylococcus saprophyticus , bacteria , adhesion , aeromonas veronii , cell culture , shigella , aeromonas hydrophila , vibrio , aeromonas salmonicida , staphylococcus epidermidis , aeromonas , staphylococcus aureus , chemistry , biochemistry , salmonella , genetics , organic chemistry
Because of the affinity of certain bacterial species for sulphated glycoconjugates exposed on the epithelial cells of susceptible hosts, we hypothesized that sulphated exopolysaccharides of microalgae can be used in anti‐adhesive therapies against bacterial infections, both in cold‐ and warm‐blooded animals. In this study we found that adhesion of the human pathogen Helicobacter pylori to the HeLa S3 cell line, and adhesion of the fish pathogens Vibrio campbellii , V. ordalii , Streptococcus saprophyticus , and Aeromonas veronii to spotted sand bass primary tissue culture cells, can be effectively blocked with the various sulphated exopolysaccharides used.