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Antimicrobial effect of tetramethyldithiooxamide and its application as a biocide
Author(s) -
Tabakova S.V.,
Kantardjiev T.V.,
Mircheva V.V.
Publication year - 1998
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1472-765x.1998.00426.x
Subject(s) - biocide , antimicrobial , microbiology and biotechnology , bacteria , biology , chemistry , genetics , organic chemistry
Tetramethyldithiooxamide (TMDTOA) is a stable and effective inhibitor of metal corrosion. The antimicrobial effects of TMDTOA and its metal compounds were investigated with regard to their use as biocides for water treatment. Growth of a variety of strains of bacteria and yeasts was completely inhibited at 400 υmol 1 −1 TMDTOA or its metal complexes. At 100 mg 1 −1 there was a 99·99% reduction in the number of viable micro‐organisms; this activity persisted for 1–3 months. TMDTOA can be produced cheaply at 98% purity by a novel method, representing an alternative cost‐effective water treatment agent combining corrosion‐inhibiting and biocide characteristics.