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Effect of permeabilizing agents on antibacterial activity against a simple Pseudomonas aeruginosa biofilm
Author(s) -
Ayres H.M.,
Payne D.N.,
Furr J.R.,
Russell A.D.
Publication year - 1998
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1472-765x.1998.00397.x
Subject(s) - pseudomonas aeruginosa , biofilm , microbiology and biotechnology , biocide , bacteria , antibacterial activity , chemistry , antimicrobial , biology , genetics , organic chemistry
A simple Pseudomonas aeruginosa G48 biofilm on stainless steel discs provided a useful primary screen of the potentiating effects of various permeabilizing agents on antibacterial agents. Experiments with Ps. aeruginosa suspensions could not be used to predict the effects of biocides and permeabilizers on biofilms. Although antibacterial activity against biofilms was less than demonstrated in suspension tests, potentiation by some permeabilizers was still observed.