Premium
Nucleotide sequence analysis of two virulence‐associated genes in Listeria monocytogenes serotype 1/2b and comparison with the same genes in other serotypes important in human disease
Author(s) -
Vines A.,
Swaminathan B.
Publication year - 1997
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1472-765x.1997.00361.x
Subject(s) - listeriolysin o , listeria monocytogenes , serotype , cytolysin , biology , microbiology and biotechnology , nucleic acid sequence , virology , gene , peptide sequence , virulence , sequence analysis , listeria , genetics , bacteria
The nucleotide sequences of the hly and plc A genes (encoding listeriolysin, a thiol‐activated cytolysin and a non‐specific phospholipase C, respectively) were determined for two strains of Listeria monocytogenes serotype 1/2b. The deduced amino acid sequences for listeriolysin were identical for the two strains and identical to that of listeriolysin from serotype 4b. The two serotype 1/2b strains differed in one amino acid (histidine vs /asparagine) in the deduced amino acid sequence for phosopholipase C.