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Imaging basal ganglia function
Author(s) -
BROOKS DAVID J.
Publication year - 2000
Publication title -
journal of anatomy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.932
H-Index - 118
eISSN - 1469-7580
pISSN - 0021-8782
DOI - 10.1046/j.1469-7580.2000.19640543.x
Subject(s) - basal ganglia , neuroscience , indirect pathway of movement , motor function , basal ganglia disease , basal (medicine) , parkinson's disease , biology , psychology , medicine , physical medicine and rehabilitation , central nervous system , disease , pathology , endocrinology , insulin
In this review, the value of functional imaging for providing insight into the role of the basal ganglia in motor control is reviewed. Brain activation findings in normal subjects and Parkinson's disease patients are examined and evidence supporting the existence for functionally independent distributed basal ganglia‐frontal loops is presented. It is argued that the basal ganglia probably act to focus and filter cortical output, optimising the running of motor programs.