Premium
Linkage mapping of quantitative trait loci in humans: an overview
Author(s) -
GHOSH S.,
REICH T.,
MAJUMDER P. P.
Publication year - 2002
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1046/j.1469-1809.2002.00124.x
Subject(s) - linkage (software) , quantitative trait locus , trait , genetic linkage , family based qtl mapping , biology , association mapping , computational biology , evolutionary biology , genetics , computer science , gene mapping , gene , genotype , single nucleotide polymorphism , chromosome , programming language
In this article, we provide an overview of the different statistical procedures that have been developed for linkage mapping of quantitative trait loci. We outline the model assumptions, the data requirements and the underlying tests for linkage for the different methods.