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The human dendritic cell marker CD83 maps to chromosome 6p23
Author(s) -
BERCHTOLD S.,
JONES T.,
MÜHLZÜRBES P.,
SHEER D.,
SCHULER G.,
STEINKASSERER A.
Publication year - 1999
Publication title -
annals of human genetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.537
H-Index - 77
eISSN - 1469-1809
pISSN - 0003-4800
DOI - 10.1046/j.1469-1809.1999.6320181.x
Subject(s) - chromosome , biology , metaphase , genetics , gene , microbiology and biotechnology
The chromosomal localization of the human CD83 gene was determined using somatic cell hybrids, a radiation hybrid mapping panel and FISH analysis on human metaphase chromosomes. PCR‐based analysis of a single chromosome hybrid panel identified the presence of the CD83 gene on human chromosome 6 and subsequent analysis of the Genebridge4 radiation panel located the gene between AFMa192wg9 and AFMb322wd1 with a lod score of 9.2. Finally, using FISH analysis the CD83 gene was localized to chromosome 6 band p23.